Crib hardware failing is actually one of the most common causes of loss of life in cribs, Nancy Cowles, a crib basic safety advocate, told CBS Information correspondent Sandra Hughes. Actually, according to Cowles’ corporation Kids In Danger, 30 kids are killed and 1,200 are injured each year in crib accidents. And while these cribs were manufactured in China, in this case she says China isn’t to blame: The problem is the design flaws that the U.S. Manufacturers designed into the product, Cowles said. Simplicity strives to create safe products, that is our number one priority. That is why we worked with the CPSC to consider this action, Simpleness president Ken Waldman stated in a statement.Methods Patients Eligible individuals were at least 18 years and had previously untreated stage III or stage IV melanoma with measurable lesions, an Eastern Cooperative Oncology Group performance status of 0 or 1 ,17 and a full life span of 16 weeks or even more. The baseline serum lactate dehydrogenase level didn’t affect eligibility. Individuals were ineligible if they had received any prior treatment for metastatic disease. Patients who received prior adjuvant therapy weren’t excluded. Concomitant treatment with immunosuppressive brokers or long-term usage of systemic glucocorticoids was not allowed. Patients had been also ineligible if indeed they had evidence of mind metastasis , primary ocular or mucosal melanoma, or autoimmune disease. Study Oversight The protocol was approved by the appropriate institutional review boards or independent ethics committees.