A biopharmaceutical organization focused on discovering.

, a biopharmaceutical organization focused on discovering, developing and commercializing cancer therapeutics, today announced that preclinical data from its translational study system and antibody pipeline will become offered during six poster periods at the American Association for Malignancy Research 101st Annual Meeting 2010 being kept April 17-21, 2010, in Washington, D.C. Robinson, Ph.D., senior vice president, translational medicine, AVEO Pharmaceuticals. .. AVEO Pharmaceuticals to present preclinical data from translational study platform at AACR 2010 AVEO Pharmaceuticals, Inc.Our results also suggest that in sufferers with macronodular adrenal hyperplasia, overt hypercorticolism, and unsuppressed plasma corticotropin levels, corticotropin secretion by the adrenal glands should be considered and explored by sampling the adrenal veins instead of by catheterizing the inferior petrosal sinus. This hypothesis is backed by our in vitro results: conditioned medium from hyperplastic adrenal explants stimulated the production of corticosterone in cultured rat adrenocortical cells, an impact that was inhibited by an MC2R-receptor antagonist, indicating that intraadrenal corticotropin is actually bioactive; corticotropin-receptor antagonists reduced the production of cortisol in hyperplastic explants.