The mean LDL cholesterol level was 141 mg per deciliter . Most patients were getting statin therapy for the primary avoidance of atherosclerotic vascular disease. All individuals received a consistent statin dosage through the entire scholarly study. Serum Lipoprotein Levels Degrees of serum LDL cholesterol at week 12 were reduced from mean baseline levels, which were between 138 and 144 mg per deciliter , to 127, 113, 99, and 94 mg per deciliter The proportions of patients who got an LDL cholesterol rate of less than 100 mg per deciliter were 8, 24, 28, and 36 mg per deciliter in the placebo group and the low-dose, medium-dose, and high-dose eprotirome groups, respectively.Kala-azar is certainly fatal if still left untreated. Around 300,000 instances occur per year in 70 endemic countries. Estimates suggest 30,000 fresh cases per year in Africa, with amounts increasing during an epidemic sharply. Existing monotherapies are toxic, costly, and challenging to administer, and the treatment duration is long, requiring extended hospital stays. Efficacious and cost-effective remedies as well as avoidance of relapse play a critical role in the reduced amount of disease reservoir, forming a vital part of disease control. In addition, co-infections of HIV and kala-azar is a growing problem and renders treatment more challenging for both diseases.