Acute Angle-Closure Glaucoma Prognosis and Prevention Regular eye examinations with an ophthalmologist may identify those who are at risk for acute angle-closure glaucoma. In some those who are at high risk, a laser iridotomy could be performed to avoid an attack of acute angle-closure glaucoma. If a patient has developed primary severe angle-closure in a single eye, the ophthalmologist might suggest laser iridotomy in the other eye to avoid an attack. The prognosis for acute angle-closure glaucoma is favorable with early treatment and detection. Vision loss can occur without prompt treatment. If discomfort and/or decreased eyesight occur, the patient should look for professional treatment from an ophthalmologist promptly.Secondary and Additional Efficacy Outcomes The rates of most three prespecified secondary composite outcomes were significantly lower with high-dose edoxaban than with warfarin ; there have been no significant differences between low-dosage edoxaban and warfarin in the rates of these outcomes. Treatment with edoxaban was connected with lower annualized rates of loss of life from cardiovascular causes than was warfarin: 3.17 percent with warfarin, in comparison with 2.74 percent with high-dose edoxaban and 2.71 percent with low-dosage edoxaban , with findings in an identical direction for the death rate from any cause.