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AIDS professionals develop accurate computer simulation to describe drug effects first Pooling data from thousands of assessments of the antiviral activity of more than 20 commonly utilized anti-HIV medications, AIDS experts in Johns Hopkins and Harvard universities are suffering from what they say is the first accurate pc simulation to describe drug effects. Already, the model clarifies how and just why some treatment regimens fail in a few patients who lack evidence of drug resistance. Researchers say their model is based on specific drugs, precise dosages prescribed, and on real-globe variation in how well sufferers follow prescribing guidelines.